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Acepromazine has been used for years as a sedative for calming a dog down for thunderstorms, grooming appointments, car rides and visits to the veterinarian.It has gone out of favor for many of these situations, not so much because of safety concerns, but due to it being ineffective.This medication can cause a decrease in blood pressure but serious side effects are uncommon.The trouble with any medication is that there are potential side effects and you have to weigh the risk versus the benefit.I had been giving her Benadryl for awhile..seemed ok with it …but now it’s not having the calming effect on her as it used to and her grooming day is a nightmare!!We have to muzzle her and myself and husband have to hold her down(well try to hold her) so the groomer can try to get some hair off…problem is her two front legs are a mess…tons of hair on them…she WON’T let the groomer near them it’s awful. Hi Lorie, It’s heartbreaking to hear how Abby responds to her grooming appointments.I talked to my Vet and he give me meds for her..”ACEPROMAZINE”…I am SCARED to death to give them to her…went online to read up on this med and there are too many bad comments from other people who have used this on their dogs with NOT good results… The response your little girl is having is fear and anxiety and Benadryl is rarely effective at calming a dog down.What is your opinion on this med and do you have any idea on anything us I could give her? It is unfair to her to put her through that stress without helping her feel better.

If an animal is suffering and medication would help reduce the suffering, we need to weigh the risks carefully.What I have found with acepromazine is that the sedation is effective when a dog isn’t stressed.Using Prescription Medications Calming Your Dog without Medication Community Q&A Sedation is a relaxed, calm or tranquil state induced after the administration of drugs.When a dog is sedated, he becomes more docile and can easily be handled, making it less stressful for the dog when procedures like grooming and veterinary examinations are being done.Without sedation, stressful situations can lead to restlessness, and when a dog is restless it is more prone to hurt itself, not eat, hide and hurt or bite other people and animals.

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